8-Bromo-cGMP, sodium salt
Cat. No. 1089
Chemical Name: 8-Bromoguanosine cyclic 3',5'-monophosphate sodium salt
Biological ActivityMembrane permeable cGMP analog that activates protein kinase G (PKG). 4.3-fold more potent than cGMP in activating PKG1α and promotes relaxation of tracheal and vascular smooth muscle tissue in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Sekhar et al (1992) Relaxation of pig coronary arteries by new and potent cGMP analogs that selectively activate type 1α, compared with type 1β, cGMP-dependent protein kinase. Mol.Pharmacol. 42 103. PMID: 1321950.
Buchan et al (1991) Modulation of agonist-induced calcium mobilisation in bovine aortic endothelial cells by phorbol myristate acetate and cyclic AMP but not cyclic GMP. Br.J.Pharmacol. 104 361. PMID: 1665733.
Ignarro et al (1974) Stimulation of phagocytic release of neutral protease from human neutrophils by cholinergic amines and cyclic 3',5'-guanosine monophosphate. J.Immunol. 112 210. PMID: 4359834.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses 8-Bromo-cGMP, sodium salt from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: 8-Bromo-cGMP, sodium salt, supplier, cGMP, analog, activates, PKG, protein, kinase, G, activator, Tocris Bioscience, G Protein (Heterotrimeric) products
Find multiple products by catalog number
New Products in this Area
Activator of STING-dependent signaling3',3'-cGAMP sodium salt
STING agonist2',3'-cGAMP sodium salt
Endogenous high affinity STING agonistc-Di-AMP sodium salt
Endogenous STING and DDX41 agonist; activates STING-dependent signalingc-Di-GMP sodium salt
Endogenous STING and DDX41 agonist; activates STING-dependent signalingCPYPP
DOCK2-Rac1 interaction inhibitor
October 30 - November 3, 2016
Boston, MA, USA