BU 226 hydrochloride

Cat. No. 1091

BU 226 hydrochloride C12H11N3.HCl [1186195-56-1]

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Chemical Name: 2-(4,5-Dihydroimidazol-2-yl)isoquinoline hydrochloride

Biological Activity

A high affinity ligand for I2 imidazoline sites (Ki = 2.7 nM) with very high selectivity (> 2000-fold) over α2-adrenoceptors (Ki = 6700 nM).

Technical Data

Soluble to 100 mM in water
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Hudson et al (1999) Novel selective compounds for the investigation of imidazoline receptors. Ann.N.Y.Acad.Sci. 881 81. PMID: 10415900.

Lione et al (1997) BU226: A selective ligand for rat brain imidazoline I2 sites. Soc.Neurosci.Abstr. 23 695.28.

If you know of a relevant reference for BU 226 hydrochloride please let us know.

Citations are publications that use Tocris products. Selected citations for BU 226 hydrochloride include:

Gründemann et al (2002) Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells. Br J Pharmacol 137 910. PMID: 12411423.

Do you know of a great paper that uses BU 226 hydrochloride from Tocris? If so please let us know.

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Keywords: BU 226 hydrochloride, supplier, Potent, selective, I2, ligands, Imidazoline, Receptors, BU226, hydrochloride, Tocris Bioscience, I2 Receptor products

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