BU 226 hydrochloride
Cat. No. 1091
Chemical Name: 2-(4,5-Dihydroimidazol-2-yl)isoquin
Biological ActivityA high affinity ligand for I2 imidazoline sites (Ki = 2.7 nM) with very high selectivity (> 2000-fold) over α2-adrenoceptors (Ki = 6700 nM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hudson et al (1999) Novel selective compounds for the investigation of imidazoline receptors. Ann.N.Y.Acad.Sci. 881 81. PMID: 10415900.
Lione et al (1997) BU226: A selective ligand for rat brain imidazoline I2 sites. Soc.Neurosci.Abstr. 23 695.28.
If you know of a relevant reference for BU 226 hydrochloride please let us know.
Citations are publications that use Tocris products. Selected citations for BU 226 hydrochloride include:
Gründemann et al (2002) Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells. Br J Pharmacol 137 910. PMID: 12411423.
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