Zinc protoporphyrin IX

Cat. No. 0746

Zinc protoporphyrin IX C34H32N4O4Zn

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Chemical Name: 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid, zinc complex

Biological Activity

Inhibitor of heme oxygenase, which generates the putative neurotransmitter CO.

Technical Data

Soluble to 50 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193. PMID: 9226997.

Luo and Vincen (1994) Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo. Eur.J.Pharmacol. 267 263. PMID: 7522180.

Verma et al (1993) Carbon monoxide a putative neural messenger. Science 259 381. PMID: 7678352.

Brune and Ullrich (1987) Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol.Pharmacol. 32 497. PMID: 2890093.

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Citations are publications that use Tocris products.

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