Zinc protoporphyrin IX
Cat. No. 0746
Chemical Name: 7,12-Diethenyl-3,8,13,17-tetramethy
Biological ActivityInhibitor of heme oxygenase, which generates the putative neurotransmitter CO.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193. PMID: 9226997.
Luo and Vincen (1994) Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo. Eur.J.Pharmacol. 267 263. PMID: 7522180.
Verma et al (1993) Carbon monoxide a putative neural messenger. Science 259 381. PMID: 7678352.
Brune and Ullrich (1987) Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol.Pharmacol. 32 497. PMID: 2890093.
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