ZAPA sulfate

Cat. No. 0180

ZAPA sulfate C4H6N2O2S.H2SO4 [371962-01-5]

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Chemical Name: (Z)-3-[(Aminoiminomethyl)thio]prop-2-enoic acid sulfate

Biological Activity

More potent than either GABA or muscimol as an agonist at low affinity GABAA receptors and is thus a useful ligand to investigate GABA receptors linked to benzodiazepine receptors. Also a GABAA-ρ receptor antagonist.

Technical Data

M.Wt:
244.24
Formula:
C4H6N2O2S.H2SO4
Solubility:
Soluble to 10 mM in water
Storage:
Store at RT
CAS No:
371962-01-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Johnston (1996) GABAC receptors: relatively simple transmitter-gated ion channels? TiPS 17 319. PMID: 8885697.

Holden-Dye and Walker (1988) ZAPA, (Z)-3-[(aminoiminomethyl)thio]-2-propenoic acid hydrochloride, a potent agonist at GABA-receptors on the Ascaris muscle cell. Br.J.Pharmacol. 95 3. PMID: 2851353.

Allan et al (1986) Isothiouronium compounds as γ-aminobutyric acid agonists. Br.J.Pharmacol. 88 379. PMID: 3015310.

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Keywords: ZAPA sulfate, supplier, GABAC, antagonists, agonists, low, affinity, GABAA, receptors, Tocris Bioscience, GABAA Receptor Agonist products

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