Cat. No. 0416
Chemical Name: N,N-Bis-(3,4-dimethoxyphenylethyl)-
Biological ActivityA Ca2+ blocker that strikingly prolongs cardiac action potentials by inhibiting pacemaker current and K+ outward currents.
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Berger et al (1991) Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the verapamil derivative YS-035. Naunyn Schmiedebergs Arch.Pharmacol. 344 653. PMID: 1775198.
Deana et al (1984) Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions. Biochem.J. 218 899. PMID: 6721841.
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Keywords: YS-035 hydrochloride, supplier, inhibitors, inhibits, K+, outward, pacemaker, current, Potassium, Channels, Non-Selective, Tocris Bioscience, Non-selective / Other Potassium Channel products