Cat. No. 0416
Chemical Name: N,N-Bis-(3,4-dimethoxyphenylethyl)-
Biological ActivityA Ca2+ blocker that strikingly prolongs cardiac action potentials by inhibiting pacemaker current and K+ outward currents.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
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References are publications that support the products' biological activity.
Berger et al (1991) Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the verapamil derivative YS-035. Naunyn Schmiedebergs Arch.Pharmacol. 344 653. PMID: 1775198.
Deana et al (1984) Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions. Biochem.J. 218 899. PMID: 6721841.
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Keywords: YS-035 hydrochloride, supplier, inhibitors, inhibits, K+, outward, pacemaker, current, Potassium, Channels, Non-Selective, Tocris Bioscience, Non-selective / Other Potassium Channel products