WB 4101 hydrochloride
Cat. No. 0946
Chemical Name: 2-(2,6-Dimethoxyphenoxyethyl)aminom
Biological Activityα1A-adrenergic selective antagonist. Also available as part of the α1-Adrenoceptor Tocriset™.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Heible et al (1995) α and β-adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification. J.Med.Chem. 38 3415. PMID: 7658428.
Morrow and Creese (1986) Characterisation of α1-adrenergic receptor subtypes in rat brain: a re-evaluation of 3H-WB 4101 and 3H-prazosin binding. Mol.Pharmacol. 29 321. PMID: 3010073.
Green et al (1969) The synthesis and pharmacological properties of a series of 2-substituted aminomethyl-1,4-benzodioxanes. J.Med.Chem. 12 326. PMID: 5791620.
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Citations are publications that use Tocris products. Selected citations for WB 4101 hydrochloride include:
Hott et al (2012) Both α1- and β1-adrenoceptors in the bed nucleus of the stria terminalis are involved in the expression of conditioned contextual fear. Br J Pharmacol 167 207. PMID: 22506532.
Crestani et al (2008) Both alpha1 and alpha2-adrenoceptors mediate the cardiovascular responses to noradrenaline microinjected into the bed nucleus of the stria terminal of rats. Br J Pharmacol 153 583. PMID: 18037912.
Do you know of a great paper that uses WB 4101 hydrochloride from Tocris? If so please let us know.
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