Cat. No. 0757
Chemical Name: (3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester
Biological ActivityPhosphodiesterase inhibitor, selective for PDE1 (IC50 = 21 μM). Also blocks voltage-gated Na+ channels.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Molnar and Erdo (1995) Vinpocetine is as potent as phenytoin to block voltage-gated Na+ channels in rat cortical neurons. Eur.J.Pharmacol. 273 303. PMID: 7737339.
Hagiwara et al (1984) Effect of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem.Pharmacol. 33 453. PMID: 6322804.
Merck Index 12 10128.
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Keywords: Vinpocetine, supplier, PDE1, inhibitors, inhibits, Na+, channel, blockers, Phosphodiesterases, Sodium, NaV, Channels, voltage-gated, voltage-dependent, Tocris Bioscience, Voltage-gated Sodium (NaV) Channel Blocker products
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