Cat. No. 0653
Alternative Name: AH 5183
Chemical Name: (±)-trans-2-(4-Phenylpiperidinyl)cyc
Biological ActivityInhibitor of acetylcholine transport (Ki = 2 nM). Centrally active following systemic administration in vivo.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Efange et al (1997) N-hydroxyalkyl derivatives of 3β-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J.Med.Chem. 40 3905. PMID: 9397171.
Kobayashi et al (1997) Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats. Brain Res.Bull. 43 17. PMID: 9205789.
Varoqui and Erickson (1996) Active transport of acetylcholine by the human vesicular acetylcholine transporter. J.Biol.Chem. 271 27229. PMID: 8910293.
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Keywords: (±)-Vesamicol hydrochloride, supplier, AH5183, inhibitors, inhibits, ACh, transport, Acetylcholine, Transporters, Monoamine, Neurotransmitter, Tocris Bioscience, Acetylcholine Transporter Inhibitor products