Cat. No. 0498
Chemical Name: cis-(±)-3,4-Dichloro-N-methyl-N-[2-(
Biological Activityκ-opioid agonist and anticonvulsant. Perhaps acts as an NMDA antagonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
on-line. Please contact Customer Service
Sethy and Sage (1992) Modulation of release of acetylcholine from the striatum by a proposed excitatory amino acid antagonist U-54494A: comparison with known antagonists, diazepam and phenytoin. Neuropharmacology 31 111. PMID: 1348110.
Proietti et al (1991) In vitro depressant effects of U-54494A, an anticonvulsant related to kappa opioids in the hippocampus. Neuropharmacology 30 637. PMID: 1656303.
Voigtlander et al (1987) U-54494A: a unique anticonvulsant related to kappa opioid agonists. J.Pharmacol.Exp.Ther. 243 542. PMID: 2824750.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses U-54494A hydrochloride from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: U-54494A hydrochloride, supplier, agonists, κ-opioid, kappa-opioid, KOP, Receptors, OP2, Tocris Bioscience, κ Opioid Receptor Agonist products
Find multiple products by catalog number
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.