Tyrphostin B44, (-) enantiomer
Cat. No. 0578
Chemical Name: (R)-(E)-2-Cyano-3-(3',4'-dihydroxyphe
Biological ActivityPotent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), more active than the (+) enantiomer (Cat. No. 0579). Selective over ErbB2.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Gazit et al (1991) Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrophostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J.Med.Chem. 34 1896. PMID: 1676428.
If you know of a relevant reference for Tyrphostin B44, (-) enantiomer please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Tyrphostin B44, (-) enantiomer from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Tyrphostin B44, (-) enantiomer, supplier, EGFR, kinase, inhibitors, inhibits, Epidermal, Growth, Factor, Receptors, ErbB, Her, RTK, Receptor, Tyrosine, Kinases, RTKs, (-)-TyrphostinB44, Tocris Bioscience, EGFR Inhibitor products
Find multiple products by catalog number
May 17 - 19, 2017