(+)-SK&F 10047 hydrochloride
Cat. No. 1079
Chemical Name: (2S,6S,11S)-1,2,3,4,5,6-Hexahydro-6
Biological ActivityPrototypical σ1 receptor agonist. Behaviorally active in animal models of memory and stress.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Kamei et al (1996) (+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress via dopaminergic systems linked to phenytoin-regulated σ1 sites. Eur.J.Pharmacol. 309 149. PMID: 8874133.
Matsuno et al (1995) Involvement of σ1 receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats. Brain Res. 690 200. PMID: 8535837.
Walker et al (1990) Sigma receptors: biology and function. Pharmacol.Rev. 42 355. PMID: 1964225.
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