Cat. No. 1076
Chemical Name: 3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-
Biological ActivitySelective Na+, K+-ATPase inhibitor.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Croyle et al (1997) Extensive random mutagenesis analysis of the Na/K+ ATPase alpha subunit identifies known and previously unidentified amino acid residues that alter ouabain sensitivity-implications for ouabain binding. Eur.J.Biochem. 248 488. PMID: 9346307.
Hosoi et al (1997) Isoform-specific up-regulation by ouabain of Na+, K+-ATPase in cultured rat astrocytes. J.Neurochem. 69 2189. PMID: 9349566.
Marjorie et al (1997) Ouabain improves cardiac function in vivo in rats with heart failure after chronic but not acute treatment. Naunyn Schmiedebergs Arch.Pharmacol. 356 203. PMID: 9272726.
Merck Index 12 7031.
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Citations are publications that use Tocris products. Selected citations for Ouabain include:
Ismael-Badarneh et al (2015) The Role of Angiotensin II and Cyclic AMP in Alveolar Active Sodium Transport. PLoS One 10 e0134175. PMID: 26230832.
Pál et al (2015) Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity. Nat Neurosci 8 35. PMID: 26043770.
Grassin-Delyle et al (2013) The expression and relaxant effect of bitter taste receptors in human bronchi. Respir Res 14 134. PMID: 24266887.
Genda et al (2011) Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria. J Neurosci 31 18275. PMID: 22171032.
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Keywords: Ouabain, supplier, Na+K+-ATPases, inhibitors, inhibits, Ion, Pumps, Transporters, Tocris Bioscience, Na+/K+ ATPase Inhibitor products