LY 310762 hydrochloride

Cat. No. 3078

LY 310762 hydrochloride C24H27FN2O2.HCl [192927-92-7]

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Chemical Name: 1-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-one hydrochloride

Biological Activity

5-HT1D-preferring receptor antagonist (EC50 = 31 nM). Displays no activity on 5-HT transport.

Licensing Information

Sold under license from Eli Lilly and company

Technical Data

Soluble to 10 mM in water and to 100 mM in DMSO
>98 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Pullar et al (2004) The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. Eur.J.Pharmacol. 493 85. PMID: 15189767.

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Citations are publications that use Tocris products. Selected citations for LY 310762 hydrochloride include:

Conley et al (2015) Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti. Pain 352 53. PMID: 25332454.

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Keywords: LY 310762 hydrochloride, supplier, 5-HT1D-preferring, antagonists, Serotonin, Receptors, LY310762, hydrochloride, Tocris Bioscience, 5-HT1D Receptor Antagonist products

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