Cat. No. 3075
Alternative Name: GW4716
Chemical Name: 4-Hydroxy-2-[(1E)-[4-(1-methylethyl
Biological ActivitySelective agonist at estrogen-related receptors ERRβ and ERRγ. Displays selectivity over ERRα and the classical estrogen receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Ariazi and Jordan (2006) Estrogen-related receptors as emerging targets in cancer and metabolic disorders. Curr.Top.Med.Chem. 6 203. PMID: 16515477.
Wang et al (2006) X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J.Biol.Chem. 281 37773. PMID: 16990259.
Zuercher et al (2005) Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRβ and ERRγ. J.Med.Chem. 48 3107. PMID: 15857113.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses GSK 4716 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: GSK 4716, supplier, Selective, ERRγ, ERRgamma, ERRβ, ERRbeta, agonists, Estrogen, related, Receptors, GSK4716, Tocris Bioscience, Estrogen and Related Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Synthetic retinoid; induces differentiation of stem cellsSI-2 hydrochloride
Steroid receptor coactivator 3 (SRC-3) inhibitorSR 0987
T cell-specific RORγ (RORγt) agonistWAY 252623
Potent LXR agonistSR 9009
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.