Cat. No. 3071
Chemical Name: (9α,13α,14α)-3-Methoxy-17-methylmorphi
Biological ActivityNon-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Keller et al (2008) Dextromethorphan is protective against sensitized N-methyl-D-aspartate receptor-mediated excitotoxic brain damage in the developing mouse brain. Eur.J.Neurosci. 27 874. PMID: 18279363.
Choi et al (1987) Dextrorophan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on corticol neurons. J.Pharmacol.Exp.Ther. 242 713. PMID: 3039122.
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Citations are publications that use Tocris products. Selected citations for Dextromethorphan hydrobromide include:
Ghoshooni et al (2011) Milled Stress Reduces Morphine-Induced Locomotion in F2 NMRI Mice. Pharmacol Res Perspect 10 347. PMID: 24250364.
Do you know of a great paper that uses Dextromethorphan hydrobromide from Tocris? If so please let us know.
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Keywords: Dextromethorphan hydrobromide, supplier, NMDA, receptor, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Tocris Bioscience, NMDA Receptor Antagonist products