Desipramine hydrochloride

Cat. No. 3067

Desipramine hydrochloride C18H22N2.HCl [58-28-6]

Price and Availability

For Desipramine hydrochloride pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Chemical Name: 10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride

Biological Activity

Tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (Ki values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).

Technical Data

M.Wt:
302.84
Formula:
C18H22N2.HCl
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
58-28-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Select another batch:
Safety Data Sheet: View Safety Data Sheet

Zhao et al (2008) Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. Neuropsychopharmacol. 33 3190.

Torres et al (2003) Plasma membrane monoamine transporters: structure, regulation and function. Nat.Rev.Neurosci. 4 13. PMID: 12511858.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Desipramine hydrochloride include:

Bucher et al (2014) Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. J Cereb Blood Flow Metab 34 1128. PMID: 24714037.

Choi et al (2013) Changes in c-Fos Expression in the Forced Swimming Test: Common and Distinct Modulation in Rat Brain by Desipramine and Citalopram. Korean J Physiol Pharmacol 17 321. PMID: 23946692.

Do you know of a great paper that uses Desipramine hydrochloride from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: Desipramine hydrochloride, supplier, Selective, inhibitors, inhibits, noradrenaline, transporters, Transporter, NET, Adrenergic, Monoamine, Neurotransmitter, Tocris Bioscience, Adrenergic Transporter Inhibitor products

Quick Order

Find multiple products by catalog number

divider line

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

Our Cardiovascular Guide highlights over 250 products for cardiovascular research. Request copy or view PDF today.

divider line

New Products in this Area

ML 352 hydrochloride

High affinity and selective presynaptic choline transporter (CHT) inhibitor

Sign-up for new product e-alerts
divider line

LinkedIn Updates

Follow Tocris on LinkedIn

Follow us on LinkedIn!

Visit our LinkedIn page for the latest Tocris news, events and updates.