TLQP 21

Cat. No. 3051

TLQP 21 Thr-Leu-Gln-Pro-Pro-Ala-Ser-Ser-Arg-Arg-Arg-His-Phe-His-His-Ala-Leu-Pro-Pro-Ala-Arg

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Biological Activity

VGF-derived peptide; spans residues 556-576 of the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. Increases energy expenditure and prevents early phase diet-induced diabetes.

Technical Data

M.Wt:
2432.77
Formula:
C107H170N40O26
Sequence:
TLQPPASSRRRHFHHALPPAR
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
869988-94-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Severini et al (2008) TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cell death induced by serum and potassium deprivation. J.Neurochem. 104 534. PMID: 18173805.

Jethwa et al (2007) VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters. Endocrinol. 148 4044.

Bartolomucci et al (2006) TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the early phase of diet-induced obesity. Proc.Natl.Acad.Sci. USA 103 14584.

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Keywords: TLQP 21, supplier, VGF-derived, peptide, Neurotrophin, Receptors, TLQP21, Tocris Bioscience, Trk Receptor products

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