Cat. No. 3045
Alternative Names: Phenoxazole, Phenylisohydantoin
Chemical Name: 2-Amino-5-phenyl-4(5H)-oxazolone
Biological ActivityLong-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Muehlmann et al (2008) Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy. J.Pharmacol.Exp.Ther. 324 214. PMID: 17925479.
Kies and Devine (2004) Self-injurious behaviour: a comparison of caffeine and pemoline models in rats. Pharmacol.Biochem.Behav. 79 587. PMID: 15582667.
Mueller and Nyhan (1982) Pharmacologic control of pemoline induced self-injurious behavior in rats. Pharmacol.Biochem.Behav. 16 957. PMID: 6213967.
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Citations are publications that use Tocris products.
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Keywords: Pemoline, supplier, CNS, stimulant, indirect, monoamine, agonists, Dopaminergic, Dopamine, Receptors, Adrenergic, Compounds, Adrenoceptors, Serotonin, 5-HT-, 5-Hydroxytryptamine, Tocris Bioscience, Dopaminergic-Related products