Pemoline

Cat. No. 3045

Pemoline C9H8N2O2 [2152-34-3]

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Alternative Names: Phenoxazole, Phenylisohydantoin

Chemical Name: 2-Amino-5-phenyl-4(5H)-oxazolone

Biological Activity

Long-acting central stimulant that induces self-injurious behavior in rats. Acts as an indirect monoamine agonist.

Technical Data

M.Wt:
176.17
Formula:
C9H8N2O2
Solubility:
Soluble to 10 mM in ethanol with gentle warming
Purity:
>99 %
Storage:
Store at RT
CAS No:
2152-34-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Muehlmann et al (2008) Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy. J.Pharmacol.Exp.Ther. 324 214. PMID: 17925479.

Kies and Devine (2004) Self-injurious behaviour: a comparison of caffeine and pemoline models in rats. Pharmacol.Biochem.Behav. 79 587. PMID: 15582667.

Mueller and Nyhan (1982) Pharmacologic control of pemoline induced self-injurious behavior in rats. Pharmacol.Biochem.Behav. 16 957. PMID: 6213967.

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Keywords: Pemoline, supplier, CNS, stimulant, indirect, monoamine, agonists, Dopaminergic, Dopamine, Receptors, Adrenergic, Compounds, Adrenoceptors, Serotonin, 5-HT-, 5-Hydroxytryptamine, Tocris Bioscience, Dopaminergic-Related products

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