Tin protoporphyrin IX dichloride

Cat. No. 0747

Tin protoporphyrin IX dichloride C34H32Cl2N4O4Sn [14325-05-4]

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Biological Activity

A potent inhibitor of heme oxygenase. Prevents hyperbilirubinemia in neonates.

Technical Data

Soluble to 25 mM in 1eq. NaOH and to 5 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193. PMID: 9226997.

Drummond and Kappas (1981) Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of haem oxidation. Proc.Natl.Acad.Sci.U.S.A. 78 6466. PMID: 6947237.

If you know of a relevant reference for Tin protoporphyrin IX dichloride please let us know.

Citations are publications that use Tocris products. Selected citations for Tin protoporphyrin IX dichloride include:

Ye et al (2013) Astaxanthin protects against MPP(+)-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis. BMC Neurosci 13 156. PMID: 23272707.

Guimarães et al (2012) Mitochondrial uncouplers inhibit hepatic stellate cell activation. BMC Gastroenterol 12 68. PMID: 22686625.

Do you know of a great paper that uses Tin protoporphyrin IX dichloride from Tocris? If so please let us know.

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Keywords: Tin protoporphyrin IX dichloride, supplier, Heme, haem, oxygenase, inhibitors, inhibits, Oxygenases, Oxidases, Tin, protoporphyrinIX, dichloride, Tocris Bioscience, Heme Oxygenase Inhibitor products

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