2-TEDC

Cat. No. 0645

2-TEDC C16H13NO4S [132465-10-2]

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Chemical Name: 2-(1-Thienyl)ethyl 3,4-dihydroxybenzylidenecyanoacetate

Biological Activity

Potent inhibitor of 5-, 12-, and 15-lipoxygenase (IC50 values are 0.09, 0.013 and 0.5 μM respectively).

Technical Data

M.Wt:
315.34
Formula:
C16H13NO4S
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol
Purity:
>99 %
Storage:
Desiccate at +4°C
CAS No:
132465-10-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Cho et al (1991) Novel caffeic acid derivatives - extremely potent inhibitors of 12-lipoxygenase. J.Med.Chem. 34 1503. PMID: 2016727.

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Keywords: 2-TEDC, supplier, 5-lipoxygenase, 12-lipoxygenase, 15-Lipoxygenase, inhibitors, inhibits, Oxygenases, Oxidases, 5-LOX, 12-LOX, 15-LOX, Tocris Bioscience, Lipoxygenase Inhibitor products

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