Cat. No. 3017
Chemical Name: 3-[2-(Dimethylamino)ethyl]-1-methyl
Biological ActivityPotent and selective 5-HT2C agonist (IC50 values are 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). Displays high affinity for the 5-HT2B receptor (Ki = 38 nM) but acts as an inverse agonist. Active in vivo; inhibits scratching in a mouse model of OCD.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Sard et al (2005) SAR of psilocybin analogs: discovery of a selective 5-HT2C agonist. Bioorg.Med.Chem.Letts. 15 4559.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses 1-Methylpsilocin from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: 1-Methylpsilocin, supplier, Potent, selective, 5-HT2C, agonists, Serotonin, Receptors, Tocris Bioscience, 5-HT2C Receptor Agonist products
Find multiple products by catalog number
One Day Symposium
March 1, 2017
Amsterdam, The Netherlands