Cat. No. 3017
Chemical Name: 3-[2-(Dimethylamino)ethyl]-1-methyl
Biological ActivityPotent and selective 5-HT2C agonist (IC50 values are 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). Displays high affinity for the 5-HT2B receptor (Ki = 38 nM) but acts as an inverse agonist. Active in vivo; inhibits scratching in a mouse model of OCD.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Sard et al (2005) SAR of psilocybin analogs: discovery of a selective 5-HT2C agonist. Bioorg.Med.Chem.Letts. 15 4559.
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Keywords: 1-Methylpsilocin, supplier, Potent, selective, 5-HT2C, agonists, Serotonin, Receptors, Tocris Bioscience, 5-HT2C Receptor Agonist products