Cat. No. 0635
Chemical Name: N,N'-1,10-Decanediylbisguanidine sulfate
Biological ActivityAn effective non-competitive NMDA receptor antagonist in vivo and in vitro; may bind to more than one site, one of which is the polyamine site.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Reynolds (1992) Interactions between zinc and spermidine on the N-methyl-D-aspartate receptor complex: clues to the mechanism of action of 1,10-bis(guanidino)decane and pentamidine. J.Pharmacol.Exp.Ther. 263 632. PMID: 1432693.
Reynolds et al (1991) 1,10-Bis(guanidino)decane inhibits N-methyl-D-aspartate responses in vitro and in vivo. J.Pharmacol.Exp.Ther. 259 626. PMID: 1658306.
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Keywords: Synthalin sulfate, supplier, Non-competitive, NMDA, antagonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Tocris Bioscience, NMDA Receptor Antagonist products