Cat. No. 0731
Chemical Name: 4-Amino-N-(3,4-dimethyl-5-isoxazoly
Biological ActivityA selective ETA endothelin receptor antagonist (IC50 values are 600 and 2200 nM for ETA and ETB receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Chan et al (1994) Identification of a new class of ETA selective endothelin antagonists by pharmacophore directed screening. Biochem.Biophys.Res.Commun. 201 228. PMID: 8198578.
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Keywords: Sulfisoxazole, supplier, Endothelin, ETA, antagonists, Receptors, Tocris Bioscience, ETA Receptor Antagonist products