(-)-Lobeline hydrochloride

Cat. No. 1077

(-)-Lobeline hydrochloride C22H27NO2.HCl [134-63-4]

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Chemical Name: 2-[(2R,6S)-6-[(2S)-2-Hydroxyphenethyl)]-1-methyl-2-piperidinyl]acetophenone hydrochloride

Biological Activity

High affinity, partial agonist with a Ki value of 4.4 nM in rat brain.

Technical Data

M.Wt:
373.92
Formula:
C22H27NO2.HCl
Solubility:
Soluble to 50 mM in ethanol and to 10 mM in water
Storage:
Store at RT
CAS No:
134-63-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Farook et al (2009) Lobeline, a nicotinic partial agonist attenuates alcohol consumption and preference in male C57BL/6J mice. Physiol.Behav. 97 503. PMID: 19268674.

Damaj et al (1997) Pharmacology of lobeline, a nicotinic receptor ligand. J.Pharmacol.Exp.Ther. 282 410. PMID: 9223582.

Merck Index 12 5580.

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Keywords: (-)-Lobeline hydrochloride, supplier, Nicotinic, agonists, Acetylcholine, Receptors, Non-Selective, Subtypes, nAChR, partial, Tocris Bioscience, Nicotinic Receptor (Non-selective) Agonist products

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