Cat. No. 1384
Chemical Name: 4-[[[(3-Chlorophenyl)amino]carbonyl
Biological ActivitySelective muscarinic M1 receptor agonist. Selectivity for M1 over other muscarinic receptor types appears to arise from a high efficacy at M1 receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Davies et al (2001) Inhibition of field stimulation-induced contractions of rabbit vas deferens by muscarinic receptor agonists: selectivity of McN-A-343 for M1 receptors. J.Pharm.Pharmacol. 53 487. PMID: 11341365.
Eglen et al (1996) Muscarinic receptor subtypes and smooth muscle function. Pharmacol.Rev. 48 531. PMID: 8981565.
Micheletti and Schiavone (1990) Functional determination of McN-A-343 affinity for M1 muscarinic receptors. J.Pharmacol.Exp.Ther. 253 310. PMID: 1691785.
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Keywords: McN-A 343, supplier, Selective, M1, muscarinic, agonists, Receptors, Acetylcholine, ACh, McNA343, Tocris Bioscience, M1 Receptor Agonist products
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