D-erythro-Sphingosine (synthetic)

Cat. No. 0633

D-erythro-Sphingosine (synthetic) C18H37NO2 [123-78-4]

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Chemical Name: trans-D-erythro-2-Amino-4-octadecene-1,3-diol

Biological Activity

Inhibitor of protein kinase C and calmodulin-dependent enzymes, but may stimulate mast cells by activation of protein kinase C.

Technical Data

M.Wt:
299.5
Formula:
C18H37NO2
Solubility:
Soluble to 5 mM in DMSO and to 50 mM in ethanol
Storage:
Store at -20°C
CAS No:
123-78-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Grossman (1990) Sphingosine inhibition and promotion of histamine release from isolated rat mast cells. Agents Actions 31 171. PMID: 1707581.

Merrill et al (1989) Structural requirements for long-chain (sphingoid) base inhibition of protein kinase C in vitro and for the cellular effects of these compounds. Biochemistry 28 3138. PMID: 2742830.

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Keywords: D-erythro-Sphingosine (synthetic), supplier, Protein, kinase, C, inhibitors, inhibits, PKC, Kinases, Tocris Bioscience, Protein Kinase C Inhibitor products

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