Zolantidine dimaleate

Cat. No. 1070

Zolantidine dimaleate C22H27N3OS.2C4H4O4 [104076-39-3]

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Chemical Name: N-[3-[3-(1-Piperidinylmethyl)phenoxy]propyl]-2-benzothiazolamine dimaleate

Biological Activity

A potent, selective and brain penetrating H2 receptor antagonist.

Licensing Information

Sold with the permission of GlaxoSmithKline

Technical Data

M.Wt:
613.68
Formula:
C22H27N3OS.2C4H4O4
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at +4°C
CAS No:
104076-39-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Coruzzi et al (1996) Cardiac and gastric effects of histamine H2 receptor antagonists: no evidence for a correlation between lipophilicity and receptor affinity. Br.J.Pharmacol. 118 1813. PMID: 8842448.

Coruzzi et al (1994) Activity of the new histamine H2-receptor antagonist zolantidine at cardiac and gastric H2 receptors. Pharmacology 48 69. PMID: 7907797.

Calcutt et al (1988) Zolantidine (SK&F 95282) is a potent selective brain penetrating histamine H2-receptor antagonist. Br.J.Pharmacol. 93 69. PMID: 2894879.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Zolantidine dimaleate include:

Porter et al (2005) Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther 315 711. PMID: 16040814.

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Keywords: Zolantidine dimaleate, supplier, Potent, centrally, active, H2, antagonists, Receptors, Histamine, histaminergic, GlaxoSmithKline, GSK, Tocris Bioscience, Histamine H2 Receptor Antagonist products

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