L-Serine

Cat. No. 0227

L-Serine C3H7NO3 [56-45-1]

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Chemical Name: β-Hydroxyalanine

Biological Activity

Endogenous agonist at the inhibitory glycine receptor. D-Serine (Cat. No. 0226) also available.

Technical Data

M.Wt:
105.09
Formula:
C3H7NO3
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
56-45-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Schmeiden and Betz (1995) Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol.Pharmacol. 48 919. PMID: 7476923.

Saitoh et al (1994) A novel antagonist, phenylbenzene ω-phosphono-α-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br.J.Pharmacol. 113 165. PMID: 7812607.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for L-Serine include:

Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1. PMID: 20552041.

Do you know of a great paper that uses L-Serine from Tocris? If so please let us know.

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Keywords: L-Serine, supplier, endogenous, glycine, receptor, agonists, GlyR, Glycine, Receptors, beta-Hydroxyalanine, b-Hydroxyalanine, β-Hydroxyalanine, Tocris Bioscience, Glycine Receptor Agonist products

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