Cat. No. 0226
Biological ActivityGlycine agonist at the NMDA receptor. L-Serine (Cat. No. 0227) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Mothet et al (2000) D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc.Natl.Acad.Sci.USA 97 4926. PMID: 10781100.
Schell et al (1997) D-Serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors. J. Neurosci. 17 1604. PMID: 9030620.
Lodge (1989) Non-competitive NMDA antagonists. The NMDA Receptor (2nd edition). Eds. G.L.Collingr 37.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for D-Serine include:
Potier et al (2010) Contribution of the d-Serine-Dependent Pathway to the Cellular Mechanisms Underlying Cognitive Aging. Front Aging Neurosci 2 1. PMID: 20552041.
Morante-Oria et al (2003) Subpallial origin of a population of projecting pioneer neurons during corticogenesis. Proc Natl Acad Sci U S A 100 12468. PMID: 14523241.
Do you know of a great paper that uses D-Serine from Tocris? If so please let us know.
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Keywords: D-Serine, supplier, Potentiator, glycine, site, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Tocris Bioscience, NMDA Receptor products
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