Saclofen

Cat. No. 0246

Saclofen C9H12ClNO3S [125464-42-8]

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Chemical Name: (RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid

Biological Activity

Selective antagonist at GABAB receptors.

Technical Data

M.Wt:
249.72
Formula:
C9H12ClNO3S
Solubility:
Soluble to 10 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
125464-42-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Jane et al (1990) Use of the neonatal rat spinal cord in studies of the GABAB receptor. GABAB receptors in Mammalian Function. 42b.

Bowery (1989) GABAB receptors and their significance in mammalian pharmacology. TiPS 10 401. PMID: 2559518.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Saclofen include:

Atasoy et al (2014) A genetically specified connectomics approach applied to long-range feeding regulatory circuits. Nat Neurosci 17 1830. PMID: 25362474.

Melyan et al (2004) Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors. J Neurosci 24 4530. PMID: 15140923.

Do you know of a great paper that uses Saclofen from Tocris? If so please let us know.

View Related Products by Product Action

Keywords: Saclofen, supplier, Selective, GABAB, antagonists, Receptors, Tocris Bioscience, GABAB Receptor Antagonist products

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