RU 24969 hemisuccinate

Cat. No. 0912

RU 24969 hemisuccinate C14H16N2O.C4H6O4 [66611-27-6]

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Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate

Biological Activity

Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.

Technical Data

M.Wt:
287.34
Formula:
C14H16N2O.½C4H6O4
Solubility:
Soluble to 50 mM in DMSO and to 30 mM in water
Purity:
>99 %
Storage:
Store at RT
CAS No:
66611-27-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129. PMID: 10837852.

Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412. PMID: 8450834.

Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antidopaminergic properties. Eur.J.Med.Chem. 22 33.

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Citations are publications that use Tocris products. Selected citations for RU 24969 hemisuccinate include:

Lawson et al (2016) Effects of Oxytocin on Serotonin 1B Agonist-induced Autism-like Behavior in Mice Behavioural Brain Research 314 52. PMID: 27439030.

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Keywords: RU 24969 hemisuccinate, supplier, 5-HT1B/1A, agonists, Serotonin, Receptors, RU24969, hemisuccinate, C14H16N2O.0.5C4H6O4, Tocris Bioscience, 5-HT1A Receptor Agonist products

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