Rosmarinic acid

Cat. No. 0630

Rosmarinic acid C18H16O8 [20283-92-5]

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Chemical Name: [R-(+)]-α-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxybenzenepropanoic acid

Biological Activity

Anti-inflammatory, cytostatic and antiviral. Also displays agonist activity at GPR35.

Technical Data

Soluble to 100 mM in water
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Deng et al (2012) Multiple tyrosine metabolites are GPR35 agonists. Sci.Rep. 2 373. PMID: 22523636.

Sahu et al (1999) Inhibition of complement by covalent attachment of rosmarinic acid to activated C3b. Biochem.Pharmacol. 57 1439. PMID: 10353266.

Rampart et al (1986) Complement-dependent stimulation of prostacyclin biosynthesis: inhibition by rosmarinic acid. Biochem.Pharmacol. 35 1397. PMID: 3516156.

Van Kessel et al (1986) Rosmarinic acid inhibits external oxidative effects of human polymorphonuclear granulocytes. Agents Actions. 17 375. PMID: 3962787.

Bult et al (1985) Modification of endotoxin-induced haemodynamic and haematological changes in the rabbit by methylprednisolone, F(ab')2 fragments and rosmarinic acid. Br.J.Pharmacol. 84 317. PMID: 3838489.

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Keywords: Rosmarinic acid, supplier, Anti-inflammatory, cytostatic, anti-viral, Tocris Bioscience, Antiviral products

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