Cat. No. 1394

(RS)-3,4-DCPG C10H9NO6 [176796-64-8]

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Chemical Name: (RS)-3,4-Dicarboxyphenylglycine

Biological Activity

Systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG (Cat. No. 1302) or (R)-3,4,-DCPG (Cat. No. 1395).

Technical Data

Soluble to 50 mM in water
>99 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Moldrich et al (2001) Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 40 732. PMID: 11311902.

Thomas et al (1998) Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. Neuropharmacology 37 1223. PMID: 9849660.

Thomas et al (1997) Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 338 111. PMID: 9455991.

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Citations are publications that use Tocris products.

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Keywords: (RS)-3,4-DCPG, supplier, Potent, systemically, active, anticonvulsant, Racemate, Glutamate, Ionotropic, Non-Selective, iGlur, Receptors, Group, III, mGluR8, mGlu8, Metabotropic, antagonists, Tocris Bioscience, Non-selective Ionotropic Glutamate Antagonist products

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