Quipazine dimaleate

Cat. No. 0629

Quipazine dimaleate C13H15N3.2C4H4O4 [150323-78-7]

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Chemical Name: 2-(1-Piperazinyl)quinoline dimaleate

Biological Activity

Selective 5-HT3 receptor agonist. Also displays antagonist activity at peripheral 5-HT3 receptors. [3H]-Quipazine labels 5-HT3 sites in the cortical membranes.

Technical Data

Soluble to 100 mM in water
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Sharif et al (1991) Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. Br.J.Pharmacol. 102 919. PMID: 1830236.

Peroutka and Hamik (1988) [3H]Quipazine labels 5-HT3 recognition sites in rat cortical membranes. Eur.J.Pharmacol. 148 297. PMID: 3378579.

Ireland and Tyers (1987) Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 90 229. PMID: 3814920.

If you know of a relevant reference for Quipazine dimaleate please let us know.

Citations are publications that use Tocris products. Selected citations for Quipazine dimaleate include:

Hutchinson et al (2012) Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. Br J Pharmacol 37 321. PMID: 21956448.

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Keywords: Quipazine dimaleate, supplier, 5-HT3, agonists, Serotonin, Receptors, Tocris Bioscience, 5-HT3 Receptor Agonist products

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5-HT Scientific Review

Written by N. Barnes & J. Neumaler

5-HT Receptors Scientific Review

Our 5-HT review summarizes the serotonin receptor subtypes and highlights their importance in mediating various physiological & pharmacological processes. Request copy or view PDF today.

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