iso-PPADS tetrasodium salt

Cat. No. 0683

iso-PPADS tetrasodium salt C14H10N3Na4O12PS2 [207572-67-6]

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Chemical Name: Pyridoxalphosphate-6-azophenyl-2',5'-disulfonic acid tetrasodium salt

Biological Activity

P2X-purinoceptor antagonist (pKi = 6.5) with similar activity to PPADS (Cat. No. 0625).

Technical Data

M.Wt:
599.3
Formula:
C14H10N3Na4O12PS2
Solubility:
Soluble to 100 mM in water
Storage:
Desiccate at -20°C
CAS No:
207572-67-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Connolly (1995) Differentiation by pyridoxal 5-phosphate, PPADS and isoPPADS between responses mediated by UTP and those evoked by α,β-methylene-ATP on rat sympathetic ganglia. Br.J.Pharmacol. 114 727. PMID: 7735699.

Khakh et al (1994) Estimates of antagonist affinities at P2X purinoceptors in rat vas deferens. Eur.J.Pharmacol. 263 301. PMID: 7843268.

Trezise et al (1994) The use of antagonists to characterize the receptors mediating depolarization of the rat isolated vagus nerve by α,β-methylene adenosine 5'-triphosphate. Br.J.Pharmacol. 112 282. PMID: 8032652.

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Keywords: iso-PPADS tetrasodium salt, supplier, P2X, antagonists, Receptors, Purinergic, purinoceptors, Tocris Bioscience, Purinergic (P2X) Receptor Antagonist products

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