iso-PPADS tetrasodium salt
Cat. No. 0683
Chemical Name: Pyridoxalphosphate-6-azophenyl-2',5'-
Biological ActivityP2X-purinoceptor antagonist (pKi = 6.5) with similar activity to PPADS (Cat. No. 0625).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Connolly (1995) Differentiation by pyridoxal 5-phosphate, PPADS and isoPPADS between responses mediated by UTP and those evoked by α,β-methylene-ATP on rat sympathetic ganglia. Br.J.Pharmacol. 114 727. PMID: 7735699.
Khakh et al (1994) Estimates of antagonist affinities at P2X purinoceptors in rat vas deferens. Eur.J.Pharmacol. 263 301. PMID: 7843268.
Trezise et al (1994) The use of antagonists to characterize the receptors mediating depolarization of the rat isolated vagus nerve by α,β-methylene adenosine 5'-triphosphate. Br.J.Pharmacol. 112 282. PMID: 8032652.
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Citations are publications that use Tocris products. Selected citations for iso-PPADS tetrasodium salt include:
Schneider et al (2015) Extracellular nucleotides as novel, underappreciated pro-metastatic factors that stimulate purinergic signaling in human lung cancer cells. Am J Physiol Renal Physiol 14 201. PMID: 26597723.
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Keywords: iso-PPADS tetrasodium salt, supplier, P2X, antagonists, Receptors, Purinergic, purinoceptors, Tocris Bioscience, Purinergic (P2X) Receptor Antagonist products