Cat. No. 1390
Chemical Name: (1R,5S)-1,2,3,4,5,6-hexahydro-1,5-m
Biological ActivityA potent, selective agonist at neuronal nicotinic receptors. Acts as a partial agonist at β2-containing nicotinic receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Happe et al (1994) Localization of nicotinic cholinergic receptors in rat brain: autoradiographic studies with [3H]cytisine. Neuroscience 62 929. PMID: 7870314.
Papke et al (1994) Partial agonist properties of cytisine on neuronal nicotinic receptors containing the β2 subunit. Mol.Pharmacol. 45 142. PMID: 8302273.
Reavill et al (1990) Behavioural and pharmacokinetic studies on nicotine, cytisine and lobeline. Neuropharmacology 29 619. PMID: 2385332.
If you know of a relevant reference for (-)-Cytisine please let us know.
Citations are publications that use Tocris products. Selected citations for (-)-Cytisine include:
Li et al (2010) Cytisine induces autonomic cardiovascular responses via activations of different nicotinic receptors. Auton Neurosci 154 14. PMID: 19887306.
Do you know of a great paper that uses (-)-Cytisine from Tocris? If so please let us know.
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Keywords: (-)-Cytisine, supplier, Potent, selective, neuronal, nicotinic, agonists, Acetylcholine, Receptors, Non-Selective, Subtypes, nAChR, Tocris Bioscience, Nicotinic Receptor (Non-selective) Agonist products
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