2-[1-(4-Piperonyl)piperazinyl]benzothiazole

Cat. No. 0736

2-[1-(4-Piperonyl)piperazinyl]benzothiazole C19H19N3O2S [155106-73-3]

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Biological Activity

5-HT4 receptor agonist with moderate activity as a 5-HT3 antagonist. Has no affinity at 5-HT1 or dopamine D2 receptors. Potential gastrokinetic agent.

Technical Data

M.Wt:
353.44
Formula:
C19H19N3O2S
Solubility:
Soluble to 10 mM in DMSO with gentle warming
Storage:
Store at RT
CAS No:
155106-73-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis is currently unavailable
on-line. Please contact Customer Service

Monge et al (1994) Synthesis of 2-piperazinybenzothiazole and 2-piperazinylbenzoxazole derivatives with 5-HT3 antagonist and 5-HT4 agonist properties. J.Med.Chem. 37 1320. PMID: 8176710.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for 2-[1-(4-Piperonyl)piperazinyl]benzothiazole include:

Gill et al (2008) Serotonin modifies cytoskeleton and brush-border membrane architecture in human intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol 295 G700. PMID: 18669621.

Do you know of a great paper that uses 2-[1-(4-Piperonyl)piperazinyl]benzothiazole from Tocris? If so please let us know.

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Keywords: 2-[1-(4-Piperonyl)piperazinyl]benzothiazole, supplier, 5-HT4, agonists, 5-HT3, antagonists, Serotonin, Receptors, 5-Hydroxytryptamine, 5-HT, Tocris Bioscience, 5-HT4 Receptor Agonist products

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