Pilocarpine hydrochloride

Cat. No. 0694

Pilocarpine hydrochloride C11H16N2O2.HCl [54-71-7]

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Chemical Name: (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride

Biological Activity

Muscarinic agonist.

Technical Data

M.Wt:
244.72
Formula:
C11H16N2O2.HCl
Solubility:
Soluble to 75 mM in DMSO and to 100 mM in water
Purity:
>98 %
Storage:
Desiccate at RT
CAS No:
54-71-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Wang et al (1999) Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current. Br.J.Pharmacol. 126 1725. PMID: 10372814.

Brown and Taylor (1996) Muscarinic receptor agonists and antagonists. The Pharmacological Basis of Therapeutics. Eds Goo Chapter 7, p147.

ten Berge et al (1996) Differences in the prejunctional effects of methacholine and pilocarpine on the release of endogenous acetylcholine from guinea-pig trachea. Naunyn Schmiedebergs Arch.Pharmacol. 354 606. PMID: 8938659.

Merck Index 12 7578.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Pilocarpine hydrochloride include:

Tallarida et al (2012) Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay. Amino Acids 42 2521. PMID: 21850438.

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Keywords: Pilocarpine hydrochloride, supplier, Muscarinic, agonists, Receptors, Acetylcholine, ACh, Tocris Bioscience, Non-selective Muscarinic Agonist products

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