Physostigmine hemisulfate

Cat. No. 0622

Physostigmine hemisulfate C15H21N3O2.1/2H2SO4 [64-47-1]

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Chemical Name: (3aS)-cis-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol methylcarbamate hemisulfate

Biological Activity

Cholinesterase inhibitor.

Technical Data

Soluble to 100 mM in water
>98 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Millard and Broomfield (1995) Anticholinesterases: medical applications of neurochemical principles. J.Neurochem 64 1909. PMID: 7722478.

Merck Index 12 7540.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Physostigmine hemisulfate include:

Parent et al (2015) Cholinergic and ghrelinergic receptors and KCNQ channels in the medial PFC regulate the expression of palatability. Proc Natl Acad Sci U S A 9 284. PMID: 26578914.

Shin et al (2015) Muscarinic regulation of dopamine and glutamate transmission in the nucleus accumbens. Front Neurosci 112 8124. PMID: 26080439.

Galow et al (2014) Energy substrates that fuel fast neuronal network oscillations. J Neurosci 8 398. PMID: 25538552.

Huchzermeyer et al (2013) Oxygen consumption rates during three different neuronal activity states in the hippocampal CA3 network. J Cereb Blood Flow Metab 33 263. PMID: 23168532.

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Keywords: Physostigmine hemisulfate, supplier, Cholinesterase, inhibitors, inhibits, AChE, Acetylcholinesterase, Esterases, Acetylcholine, Nicotinic, Receptors, nAChR, Muscarinic, Tocris Bioscience, Cholinesterase Inhibitor products

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