Oxotremorine M

Cat. No. 1067

Oxotremorine M C11H19IN2O [3854-04-4]

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Chemical Name: N,N,N-Trimethyl-4-(2-oxo-1-pyrolidinyl)-2-butyn-1-ammonium iodide

Biological Activity

Muscarinic receptor agonist.

Technical Data

M.Wt:
322.19
Formula:
C11H19IN2O
Solubility:
Soluble to 100 mM in water
Purity:
>98 %
Storage:
Desiccate at -20°C
CAS No:
3854-04-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Kukkonen et al (1996) Functional properties of muscarinic receptor subtypes Hm1, Hm3 and Hm5 expressed in Sf9 cells using the baculovirus expression system. J.Pharmacol.Exp.Ther. 279 593. PMID: 8930161.

Birdsall et al (1978) The binding of agonists to brain muscarinic receptors. Mol.Pharmacol. 14 723. PMID: 714021.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for Oxotremorine M include:

Daigle and Caron (2012) Elimination of GRK2 from cholinergic neurons reduces behavioral sensitivity to muscarinic receptor activation. J Neurosci 32 11461. PMID: 22895728.

Buchanan et al (2010) Facilitation of long-term potentiation by muscarinic M(1) receptors is mediated by inhibition of SK channels. Neuron 68 948. PMID: 21145007.

Do you know of a great paper that uses Oxotremorine M from Tocris? If so please let us know.

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Keywords: Oxotremorine M, supplier, Muscarinic, agonists, Receptors, Acetylcholine, ACh, OxotremorineM, Tocris Bioscience, Non-selective Muscarinic Agonist products

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