Pimozide

Cat. No. 0937

Pimozide C28H29F2N3O [2062-78-4]

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Chemical Name: 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one

Biological Activity

Dopamine D2-receptor antagonist and antipsychotic which binds with very high affinity to the cloned rat 5-HT7 receptor (Ki = 0.5 nM).

Technical Data

M.Wt:
461.55
Formula:
C28H29F2N3O
Solubility:
Soluble to 20 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
2062-78-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Roth et al (1994) Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors. J.Pharmacol.Exp.Ther. 268 1403. PMID: 7908055.

Merck Index 12 7589.

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Keywords: Pimozide, supplier, D2-like, antagonists, High, affinity, 5-HT7, D2, Dopamine, Non-Selective, Receptors, Serotonin, 5-Hydroxytryptamine, dopaminergic, Tocris Bioscience, Non-selective Dopamine Antagonist products

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