MRS 2219

Cat. No. 1203

MRS 2219 C8H10NO5P [14141-47-0]

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Chemical Name: 1,5-Dihydro-3-hydroxy-8-methyl[1,3,2]dioxaphosphepino[5,6-c]pyridin-9-ol-3-oxide

Biological Activity

A selective potentiator of ATP-evoked responses at rat P2X1 receptors (EC50 = 5.9 μM).

Technical Data

Soluble to 100 mM in 1eq. NaOH
>99 %
Desiccate at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Jacobson et al (1998) A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonise activation of P2X1 receptors. J.Med.Chem. 41 2201. PMID: 9632352.

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Keywords: MRS 2219, supplier, Potentiates, P2X1-mediated, responses, P2X, Receptors, Purinergic, modulators, purinoceptors, MRS2219, Tocris Bioscience, Purinergic (P2X) Receptor products

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