SR 57227 hydrochloride

Cat. No. 1205

SR 57227 hydrochloride C10H14ClN3.HCl [77145-61-0]

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Chemical Name: 1-(6-Chloro-2-pyridinyl)-4-piperidinamine hydrochloride

Biological Activity

A high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant.

Technical Data

Soluble to 50 mM in water and to 100 mM in DMSO
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Edwards et al (1996) 5-HT3-like receptors in the rat medial prefrontal cortex: further pharmacological characterization. Brain Res. 733 21. PMID: 8891244.

Bachy et al (1993) SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo. Eur.J.Pharmacol. 237 299. PMID: 7689975.

If you know of a relevant reference for SR 57227 hydrochloride please let us know.

Citations are publications that use Tocris products. Selected citations for SR 57227 hydrochloride include:

Otvos et al (2015) Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Dent Res J (Isfahan) 7 2336. PMID: 26114334.

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Keywords: SR 57227 hydrochloride, supplier, Potent, selective, 5-HT3, agonists, Serotonin, Receptors, SR57227, hydrochloride, Tocris Bioscience, 5-HT3 Receptor Agonist products

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