4-PPBP maleate

Cat. No. 0620

4-PPBP maleate C21H27N.C4H4O4 [201216-39-9]

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Chemical Name: 4-Phenyl-1-(4-phenylbutyl)piperidine maleate

Biological Activity

σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.

Technical Data

M.Wt:
409.52
Formula:
C21H27N.C4H4O4
Solubility:
Soluble to 25 mM in ethanol and to 25 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
201216-39-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Whittemore et al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326. PMID: 9223571.

Glennon et al (1991) Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 34 3360. PMID: 1662725.

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Keywords: 4-PPBP maleate, supplier, Specific, σ, sigma, ligand, NMDA, antagonists, Receptors, Tocris Bioscience, Sigma-Related Ligand products

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