Cat. No. 0620
Chemical Name: 4-Phenyl-1-(4-phenylbutyl)piperidin
Biological Activityσ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Whittemore et al (1997) Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition. J.Pharmacol.Exp.Ther. 282 326. PMID: 9223571.
Glennon et al (1991) Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands. J.Med.Chem. 34 3360. PMID: 1662725.
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Keywords: 4-PPBP maleate, supplier, Specific, σ, sigma, ligand, NMDA, antagonists, Receptors, Tocris Bioscience, Sigma-Related Ligand products