Cat. No. 0178
Chemical Name: (RS)-3-Amino-2-(4-chlorophenyl)prop
Biological ActivitySelective GABAB antagonist. Phosphono analog of GABAB agonist baclofen (Cat. No. 0417).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Hasuo and Gallagher (1988) Comparison of antagonism by phaclofen of baclofen induced hyperpolarization and synaptically mediated late hyperpolarizing potentials recorded intracellularly from rat dorsolateral septal neurons. Neurosci.Lett. 86 77. PMID: 3362432.
Karlsson et al (1988) Phaclofen: a GABAB blocker reduced long-duration inhibition in the neocortex. Eur.J.Pharmacol. 148 485. PMID: 2838310.
Kerr et al (1987) Phaclofen: a peripheral and central baclofen antagonist. Brain Res. 405 150. PMID: 3032346.
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Keywords: Phaclofen, supplier, selective, GABAB, antagonists, Receptors, Tocris Bioscience, GABAB Receptor Antagonist products
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