Pancuronium dibromide

Cat. No. 0693

Pancuronium dibromide C35H60Br2N2O4 [15500-66-0]

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Chemical Name: 1,1'-(3α,17β-Dihydroxy-2β,5α-androstan-2β,16β-ylene) bis[1-methylpiperidinium] diacetate dibromide

Biological Activity

Nicotine (neuromuscular) antagonist. Skeletal muscle relaxant.

Technical Data

Soluble to 100 mM in water
>99 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Lowenick et al (2001) Open channel and competitive block of nicotinic receptors by pancuronium and atracurium. Eur.J.Pharmacol. 413 31. PMID: 11173060.

Maestrone et al (1994) Extracellular pancuronium affects sodium current in chick embryo sensory neurones. Br.J.Pharmacol. 111 283. PMID: 8012707.

Fryer and Maclagan (1987) Pancuronium and gallamine are antagonists for pre- and post-junctional muscarinic receptors in the guinea-pig lung. Naunyn Schmiedebergs Arch.Pharmacol. 335 367. PMID: 3600815.

Merck Index 12 7139.

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Citations are publications that use Tocris products. Selected citations for Pancuronium dibromide include:

Candelier et al (2015) A microfluidic device to study neuronal and motor responses to acute chemical stimuli in zebrafish. Invest Ophthalmol Vis Sci 5 12196. PMID: 26194888.

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Keywords: Pancuronium dibromide, supplier, Nicotinic, neuromuscular, antagonists, Acetylcholine, Receptors, Non-Selective, nAChR, skeletal, muscle, relaxant, Tocris Bioscience, Nicotinic Receptor (Non-selective) Antagonist products

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