[Ala1,3,11,15]-Endothelin

Cat. No. 1197

[Ala1,3,11,15]-Endothelin Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp

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Biological Activity

Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).

Technical Data

M.Wt:
2368
Formula:
C109H163N25O32S
Sequence:
ASASSLMDKEAVYFAHLDIIW
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
121204-87-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Nakamichi et al (1992) Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET1. Biochem.Biophys.Res.Commun. 182 144. PMID: 1310013.

Panek et al (1992) Endothelin and structurally related analogs distinguish between endothelin receptor subtypes. Biochem.Biophys.Res.Commun. 183 566. PMID: 1312833.

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Keywords: [Ala1,3,11,15]-Endothelin, supplier, Selective, ETB, agonists, Receptors, Endothelin, Tocris Bioscience, ETB Receptor Agonist products

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