Cat. No. 1197
Biological ActivitySelective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Nakamichi et al (1992) Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET1. Biochem.Biophys.Res.Commun. 182 144. PMID: 1310013.
Panek et al (1992) Endothelin and structurally related analogs distinguish between endothelin receptor subtypes. Biochem.Biophys.Res.Commun. 183 566. PMID: 1312833.
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Keywords: [Ala1,3,11,15]-Endothelin, supplier, Selective, ETB, agonists, Receptors, Endothelin, Tocris Bioscience, ETB Receptor Agonist products
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High affinity dual ETA and ETB receptor antagonist;orally bioavailable
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