NPC 15199

Cat. No. 0675

NPC 15199 C21H23NO4 [35661-60-0]

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Chemical Name: N-(9-Fluorenylmethoxycarbonyl)-L-leucine

Biological Activity

Anti-inflammatory agent; increases intracellular Ca2+ levels.

Technical Data

Soluble to 100 mM in DMSO with gentle warming
>99 %
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Jan et al (2000) NPC-15199, a novel anti-inflammatory agent, mobilizes intracellular Ca2+ in bladder female transitional carcinoma (BFTC) cells. Chin.J.Physiol. 43 29. PMID: 10857466.

Miller et al (1993) Guinea pig ileitis is attenuated by the leumidin N-(fluorenyl-9-methoxycarbonyl)leucine (NPC 15199). J.Pharmacol.Exp.Ther. 266 468. PMID: 8392562.

Burch et al (1991) N-(Fluorenyl-9-methoxycarbonyl) amino acids, a class of anti-inflammatory agents with a different mechanism of action. Proc.Natl.Acad.Sci.U.S.A. 88 355. PMID: 1824872.

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Keywords: NPC 15199, supplier, Increases, intracellular, Ca2+, levels, Calcium, Signaling, Signalling, Agents, General, anti-inflammatory, NPC15199, Tocris Bioscience, General Calcium Signaling Agent products

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