5-Nonyloxytryptamine oxalate

Cat. No. 0901

5-Nonyloxytryptamine oxalate C19H30N2O.C2H2O4 [157798-13-5]

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Biological Activity

5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Mimics polysialic acid activity, stimulates neuritogenesis, myelination and Schwann cell migration in vitro.

Technical Data

M.Wt:
392.49
Formula:
C19H30N2O.C2H2O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
157798-13-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Loers et al (2013) Nonyloxytryptamine mimics polysialic acid and modulates neuronal and glial functions in cell culture. J.Neurochem. 128 88. PMID: 23957498.

Glennon et al (1996) Binding of O-Alkyl derivatives of serotonin at human 5-HT1Dβ receptors. J.Med.Chem. 39 314. PMID: 8568822.

Glennon et al (1994) 5-(Nonyloxy)tryptamine: a novel high affinity-5-HT1Dβ serotonin receptor agonist. J.Med.Chem. 37 2828. PMID: 8071931.

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Keywords: 5-Nonyloxytryptamine oxalate, supplier, Selective, 5-HT1B, agonists, Serotonin, Receptors, Tocris Bioscience, 5-HT1B Receptor Agonist products

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