Cat. No. 0602

7-Nitroindazole C7H5N3O2 [2942-42-9]

Price and Availability

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Biological Activity

Reversible, competitive and non-selective NOS inhibitor. Monosodium salt 7-NINA (Cat. No. 0800) also available.

Technical Data

Soluble to 100 mM in DMSO and to 20 mM in ethanol
>98 %
Desiccate at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204. PMID: 9226999.

Babbedge et al (1993) Inhibition of rat cerebellar nitric oxide synthase by 7-nitroindazole and related substituted indazoles. Br.J.Pharmacol. 110 225. PMID: 7693279.

Moore et al (1993) 7-nitroindazole, an inhibitor of nitric oxide synthase, exhibits antinociceptive activity in the mouse without increasing blood pressure. Br.J.Pharmacol. 108 296. PMID: 7680591.

Moore et al (1993) Characterisation of the novel nitric oxide synthase inhibitor 7-nitroindazole and related indazoles: antinociceptive and cardiovascular effects. Br.J.Pharmacol. 110 219. PMID: 7693278.

If you know of a relevant reference for 7-Nitroindazole please let us know.

Citations are publications that use Tocris products. Selected citations for 7-Nitroindazole include:

Yuan et al (2015) Protein kinase G-regulated production of H2S governs oxygen sensing. Sci Signal 8 ra37. PMID: 25900831.

Do you know of a great paper that uses 7-Nitroindazole from Tocris? If so please let us know.

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Keywords: 7-Nitroindazole, supplier, Non-Selective, NOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Synthases, Tocris Bioscience, Non-selective NOS Inhibitor products

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